Research and Publications

Asma gained her MD at the University of London in 2009 following two years’ research into pre-eclampsia (high blood pressure in pregnancy). She also has a Masters degree in Epidemiology from the London School of Hygiene & Tropical Medicine and an MRC scholarship. She has published more than 45 peer reviewed research papers in medical journals, and many review articles and book chapters. She has been awarded many research prizes, at both national and international meetings.
Her research interests include hypertensive disease in pregnancy, multiple pregnancy, and other complications of pregnancy.

She has been awarded over 15 prizes which include:

Prize for 1st place in Histology

First place prize MB BCh Graduation year

Best Oral research Presentation, BMFMS, Perinatal Medicine, Harrogate, June 2008

Young Investigator Travel Award, ISSHP, Washington DC, September 2008

Harold Malkin Research Prize, RCOG, 2009

Best Oral Poster prize, ISUOG, Hamburg, Germany, September 2009

Young Investigator Award, British Hypertension Society Meeting, Cambridge, September 2011

Best Oral Poster prize, ISUOG, Sydney, Australia, October 2013

RECENT NEWS: International Clinical Trials’ Day 2015 – JREO Stand – Find out More

Academic Activities

Published more than 135 peer-review papers of original research in Scientific Journals
Associate Editor for the journal Biomedical Central Pregnancy and Childbirth
Reviewing for Scientific Journals, e.g. Obstetrics & Gynecology, Circulation, Ultrasound in Obstetrics and Gynecology, British Journal of Obstetrics and Gynaecology, PLOS ONE
Reviewing for Grant Funding Organisations, e.g. Wellbeing Of Women, Health and Social Care (HSC) Public Health Agency (PHA) Research and Development, Northern Ireland Chest Heart Stroke Association and National Institute for Health Research
Co-author of more than 10 book chapters and review articles
Oral presentations/Invited speaker (more than 50) in both international and national conferences, e.g. ISSHP, ISUOG, SGI, World Congress of Fetal Medicine, BMFMS
Assistant Convenor for the MRCOG Part1 course, RCOG
Co-organiser of national educational meetings, e.g. Multiple Pregnancy (RCOG)
Organisor of regional educational meetings, Basic practical ultrasound programme, management of multiple pregnancy
ISUOG Ambassador: Regular ultrasound courses in North Africa and the Middle East
Principal Investigator at St George’s Hospital for several NIHR funded studies, e.g. Non-invasive Prenatal Testing (NIPT)

Peer Reviewed Scientific Papers

135 of original research in scientific journals, including in the following high impact scientific journals:

BMJ 2016

http://www.ncbi.nlm.nih.gov/pubmed/27599496

Circulation 2017

https://www.ncbi.nlm.nih.gov/pubmed/28034902

Hypertension 2016

http://www.ncbi.nlm.nih.gov/pubmed/26962206

https://www.ncbi.nlm.nih.gov/pubmed/28461601

https://www.ncbi.nlm.nih.gov/pubmed/28893900

 

  1. Webster LM, Myers JE, Nelson-Piercy C, Harding K, Cruickshank JK, Watt-Coote I, Khalil A, Wiesender C, Seed PT, Chappell LC. Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy: A Randomized Controlled Trial. Hypertension. 2017 Sep 11. [Epub ahead of print]
  2. Foo FL, McEniery CM, Lees C, Khalil A; International Working Group on Maternal Haemodynamics. Assessment of arterial function in pregnancy: recommendations of the International Working Group on Maternal Haemodynamics. Ultrasound Obstet Gynecol 2017;50:324-31.
  3. Verlohren S, Perschel F, Thilaganathan B, Dröge L, Henrich W, Busjahn A, Khalil A. Angiogenic markers and cardiovascular indices in the prediction of hypertensive disorders of pregnancy. Hypertension 2017;69:1192-7. 
  4. Familiari A, Morlando M, Khalil A, Sonesson SE, Scala C, Rizzo G, Del Sordo G, Vassallo C, Elena Flacco M, Manzoli L, Lanzone A, Scambia G, Acharya G, D’Antonio F. Risk Factors for Coarctation of the Aorta on Prenatal Ultrasound: A Systematic Review and Meta-Analysis. Circulation 2017;135:772-85.
  5. Khalil A, Perry H, Duffy J, Reed K, Baschat A, Deprest J, Hecher K, Lewi L, Lopriore E, Oepkes D; International Collaboration to Harmonise Outcomes for Twin–Twin Transfusion Syndrome (CHOOSE). Twin-Twin Transfusion Syndrome: study protocol for developing, disseminating, and implementing a core outcome set. Trials 2017;18:325.
  6. Kalafat E, Thilaganathan B, Papageorghiou A, Bhide A, Khalil A. The Significance of Placental Cord Insertion Site in Twin Pregnancy. Ultrasound Obstet Gynecol 2017 Oct 4. doi: 10.1002/uog.18914. [Epub ahead of print]
  7. D’Antonio F, Thilaganathan B, Laoreti A, Khalil A. On behalf of the Southwest Thames Obstetric Research Collaborative (STORK). Birthweight discordance and neonatal morbidity in twin pregnancies: Analysis of the STORK multiple pregnancy cohort. Ultrasound Obstet Gynecol 2017 (in press)
  8. Binder J, Monaghan C, Thilaganathan B, Morales-Roselló J, Khalil A. Cerebroplacental Ratio in Reduced Fetal Movements: Evidence for Worsening Fetal Hypoxemia. Ultrasound Obstet Gynecol 2017 Aug 7. doi: 10.1002/uog.18830. [Epub ahead of print]
  9. Binder J, Monaghan C, Thilaganathan B, Carta S, Khalil A. De-Novo Abnormal Uteroplacental Circulation in the Third Trimester: Pregnancy Outcome and Pathological Implications. Ultrasound Obstet Gynecol 2017 Jun 22. doi: 10.1002/uog.17564. [Epub ahead of print]
  10. Khalil A, Jones C, Ville Y. Congenital cytomegalovirus infection: management update. Curr Opin Infect Dis 2017;30:274-80.
  11. Meah VL, Backx K, Davenport MH; International Working Group on Maternal Haemodynamics. Functional Haemodynamic Testing in Pregnancy: Recommendations of The International Working Group on Maternal Haemodynamics. Ultrasound Obstet Gynecol. 2017 Aug 30. doi: 10.1002/uog.18890. [Epub ahead of print]
  12. Scala C, Morlando M, Familiari A, Leone Roberti Maggiore U, Ferrero S, D’Antonio F, Khalil A. Fetal Tricuspid Regurgitation in the First Trimester as a Screening Marker for Congenital Heart Defects: Systematic Review and Meta-Analysis. Fetal Diagn Ther 2017;42:1-8.
  13. Khalil A. Modified diagnostic criteria for twin-to-twin transfusion syndrome prior to 18 weeks’ gestation: time to change? Ultrasound Obstet Gynecol 2017;49:804-5.
  14. Monaghan C, Binder J, Thilaganathan B, Morales-Roselló J, Khalil A. Perinatal Loss at Term: The Role of Uteroplacental and Fetal Doppler Assessment. Ultrasound Obstet Gynecol 2017 Apr 24. doi: 10.1002/uog.17500. [Epub ahead of print]
  15. Buca DIP, Khalil A, Rizzo G, Familiari A, Di Giovanni S, Liberati M, Murgano D, Ricciardulli A, Fanfani F, Scambia G, D’Antonio F. Outcome of prenatally diagnosed fetal heterotaxy: A systematic review and meta-analysis. Ultrasound Obstet Gynecol 2017 Jun 12. doi: 10.1002/uog.17546. [Epub ahead of print]
  1. VinayagamD, Thilaganathan B, Stirrup O, Mantovani E, Khalil A. Maternal Hemodynamics in Normal Pregnancies: Reference ranges and the Role of Maternal Characteristics. Ultrasound Obstet Gynecol 2017 Apr 24. doi: 10.1002/uog.17504. [Epub ahead of print]
  2. Gustapane S, Leombroni M, Khalil A, Giacci F, Marrone L, Bascietto F, Rizzo G, Acharya G, Liberati M, D’Antonio F. Systematic review and meta-analysis of persistent left superior vena cava on prenatal ultrasound: associated anomalies, diagnostic accuracy and postnatal outcome. Ultrasound Obstet Gynecol 2016;48:701-8.
  3. Falco ML, Sivanathan J, Laoreti A, Thilaganathan B, Khalil A. Placental histopathology associated with preeclampsia: A systematic review and Meta-Analysis. Ultrasound Obstet Gynecol 2017;50:295-301.
  4. Morales-Roselló J, Khalil A, Fornés-Ferrer V, Alberola-Rubio J, Hervas-Marín D, Peralta Llorens N, Perales-Marín A. Progression of Doppler changes in early-onset small for gestational age fetuses. How frequent are the different progression sequences? J Matern Fetal Neonatal Med. 2017 Mar 27:1-9. doi: 10.1080/14767058.2017.1304910. [Epub ahead of print]
  5. Osman MW, Leone F, Nath M, Khalil A, Webb DR, Robinson TG, Mousa HA. Diurnal variation and repeatability of arterial stiffness and cardiac output measurements in the third trimester of uncomplicated pregnancy. J Hypertens 2017 Jul 14. doi: 10.1097/HJH.0000000000001482. [Epub ahead of print]
  6. Caissutti C, Familiari A, Khalil A, Flacco M, Manzoli L, Scambia G, D’Antonio F. Small fetal thymus and adverse obstetrical outcome: a systematic review and a meta-analysis. Acta Obstet Gynecol Scand 2017 (in print)
  1. Tiralongo GM, Pisani I, Vasapollo B,Khalil A, Thilaganathan B, Valensise H. Nitric oxide (NO) donors and haemodynamic changes in fetal growth restriction. Ultrasound Obstet Gynecol 2017 Mar 10. doi: 10.1002/uog.17454. [Epub ahead of print]
  2. Osman MW, Nath M, Khalil A, Webb DR, Robinson TG, Mousa HA. Longitudinal study to assess changes in arterial stiffness and cardiac output parameters among low-risk pregnant women. Pregnan Hypertens 2017 (in press)
  3. Morales-Roselló J, Khalil A, Fornés-Ferrer V, Hervas-Marín D, Peralta-Llorens N, Rubio-Moll J, Perales-Marín A. The vertebroplacental ratio as an alternative to the cerebroplacental ratio in the evaluation of the fetus at the end of pregnancy. J Matern Fetal Neonatal Med 2017:1-12.
  4. Khalil A, Morales-Rosello J, Khan N, Nath M, Agarwal P, Bhide A, Papageorghiou A, Thilaganathan B. Is cerebroplacental ratio a marker of impaired fetal growth velocity and adverse pregnancy outcome? Am J Obstet Gynecol 2017;216:606.e1-606.e10.
  5. Vinayagam D, Gutierrez J, Binder J, Mantovani E, Thilaganathan B, Khalil A. Impaired Maternal Hemodynamics in Morbidly Obese Women: A Case-control Study. Ultrasound Obstet Gynecol 2017 Feb 2. doi: 10.1002/uog.17428. [Epub ahead of print]
  6. D’Antonio F, Thilaganathan B, Dias T, Khalil A; Southwest Thames Obstetric Research Collaborative (STORK). The influence of chorionicity and gestational age at single fetal loss on the risk of preterm birth in twin pregnancies: analysis of the STORK multiple pregnancy cohort. Ultrasound Obstet Gynecol 2017 Feb 2. doi: 10.1002/uog.17426. [Epub ahead of print]
  7. Paladini D, Alfirevic Z, Carvalho JS, Khalil A, Malinger G, Martinez JM, Rychik J, Ville Y, Gardiner H; ISUOG Clinical Standards Committee. ISUOG consensus statement on current understanding of the association of neurodevelopmental delay and congenital heart disease: impact on prenatal counseling. Ultrasound Obstet Gynecol 2017;49:287-8.
  8. Morlando M, Bhide A, Familiari A, Khalil A, Morales-Roselló J, Papageorghiou AT, Carvalho JS. The association between prenatal atrioventricular septal defects and chromosomal abnormalities. Eur J Obstet Gynecol Reprod Biol 2017;208:31-5.
  9. Ghossein-Doha C, Khalil A, Lees CC. Maternal hemodynamics: a 2017 update. Ultrasound Obstet Gynecol 2017;49:10-4.
  10. Townsend R, Khalil A. Twin pregnancy complicated by selective growth restriction. Curr Opin Obstet Gynecol 2016;28:485-91.
  11. Fiona Cheong-See F, Schuit E, Arroyo-Manzano D, Khalil A, et al. Prospective risk of stillbirth and neonatal complications in twin pregnancies: A systematic review and meta-analysis. BMJ 2016;354:i4353.
  1. Melchiorre K, Sharma S, Khalil A, Thilaganathan B. Maternal cardiovascular function in normal pregnancy: evidence of maladaptation to chronic volume overload. Hypertension 2016;67:754-62.
  2. D’Antonio F, Familiari A, Thilaganathan B, Papageorghiou AT, Manzoli L, Khalil A, Bhide A. Sensitivity of first-trimester ultrasound in the detection of congenital anomalies in twin pregnancies: population study and systematic review. Acta Obstet Gynecol Scand 2016;95:1359-67.
  3. Familiari A, Bhide A, Morlando M, Scala C, Khalil A, Thilaganathan B. Mid-pregnancy fetal growth, uteroplacental Doppler indices and maternal demographic characteristics: role in prediction of stillbirth. Acta Obstet Gynecol Scand 2016;95:1313-8.
  4. Vinayagam D, Bowe S, Sheehan E, Thilaganathan B, Khalil A. Non-Invasive Haemodynamic Monitoring in Pregnancy: A Comparative Study Using Ultrasound and Bioreactance. Fetal Diagn Ther 2017;41:273-82.
  5. Marrone L, Liberati M, Khalil A, Rizzo G, Leombroni M, Buca D, Bascietto F, Gustapane S, Flacco ME, Manzoli L, Acharya G, D’Antonio F. Outcome of fetal gastro-intestinal cysts: a systematic review and meta-analysis. Prenat Diagn 2016;36:966-72.
  6. Scala C, McDonnell S, Murphy F, Leone Roberti Maggiore U, Khalil A, Bhide A, Thilaganthan B, Papageorghiou AT. Diagnostic accuracy of mid-trimester antenatal ultrasound for multicystic dysplastic kidneys. Ultrasound Obstet Gynecol 2017;50:464-9.
  7. D’Antonio F, Pagani G, Familiari A, Khalil A, Sagies TL, Malinger G, Leibovitz Z, Garel C, Moutard ML, Pilu G, Bhide A, Acharya G, Leombroni M, Manzoli L, Papageorghiou A, Prefumo F. Outcomes Associated with Isolated Agenesis of the Corpus Callosum: A Meta-analysis. Pediatrics 2016;138. pii: e20160445. doi: 10.1542/peds.2016-0445.
  8. Khalil A, Bennet S, Thilaganathan B, Paladini D, Griffiths P, Carvalho JS. Prevalence of prenatal brain abnormalities in fetuses with congenital heart disease: a systematic review. Ultrasound Obstet Gynecol 2016;48:296-307.
  9. Khalil A, Thilaganathan B. Role of uteroplacental and fetal Doppler in identifying fetal growth restriction at term. Best Pract Res Clin Obstet Gynaecol 2017;38:38-47.
  10. Stirrup OT, Khalil A, D’Antonio F, Thilaganathan B; STORK. Patterns of Second- and Third-Trimester Growth and Discordance in Twin Pregnancy: Analysis of the Southwest Thames Obstetric Research Collaborative (STORK) Multiple Pregnancy Cohort. Fetal Diagn Ther 2017;41:100-7. 
  11. D’Antonio F, Familiari A, Thilaganathan B, Papageorghiou AT, Manzoli L, Khalil A, Bhide A. Sensitivity of first-trimester ultrasound in the detection of congenital anomalies in twin pregnancies: population study and systematic review. Acta Obstet Gynecol Scand 2016;95:1359-67.
  12. Morales-Roselló J, Khalil A, Akhoundova F, Salvi S, Morlando M, Sivanathan J, Alberola-Rubio J, Hervas-Marín D, Fornés-Ferrer V, Perales-Marín A, Thilaganathan B. Fetal cerebral and umbilical Doppler in pregnancies complicated by late-onset placental abruption. J Matern Fetal Neonatal Med 2017;30:1320-4. 
  13. D’Antonio F, Khalil A, Garel C, Pilu G, Rizzo G, Lerman-Sagie T, Bhide A, Thilaganathan B, Manzoli L, Papageorghiou AT. Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal imaging (part 2): neurodevelopmental outcome. Ultrasound Obstet Gynecol 2016;48:28-37.
  14. Khalil AA, Morales-Rosello J, Morlando M, Hannan H, Bhide A, Papageorghiou A, Thilaganathan B. Is fetal cerebroplacental ratio an independent predictor of intrapartum fetal compromise and neonatal unit admission? Am J Obstet Gynecol 2015;213:54.e1-10.
  15. Bascietto F, Liberati M, Marrone L, Khalil A, Pagani G, Gustapane S, Leombroni M, Buca D, Flacco ME, Rizzo G, Acharya G, Manzoli L, D’Antonio F. Outcome of ovarian cysts diagnosed on prenatal ultrasound: a systematic review and meta-analysis. Ultrasound Obstet Gynecol 2017;50:20-31.
  16. Khalil A, Cooper E, Townsend R, Thilaganathan B. Evolution of Stage 1 Twin-to-Twin Transfusion Syndrome (TTTS): Systematic Review and Meta-Analysis. Twin Res Hum Genet 2016;19:207-16.
  1. Youssef A, D’Antonio F, Khalil A, Papageorghiou AT, Ciardulli A, Lanzone A, Rizzo G, Thilaganathan B, Pilu G. Outcome of Fetuses with Supratentorial Extra-Axial Intracranial Cysts: A Systematic Review. Fetal Diagn Ther 2016;40:1-12.
  2. Morales-Roselló J, Khalil A, Alba-Redondo A, Martinez-Triguero L, Akhoundova F, Perales-Marín A, Thilaganathan B. Protein S100β in Late-Pregnancy Fetuses with Low Birth Weight and Abnormal Cerebroplacental Ratio. Fetal Diagn Ther 2017;41:15-22.
  3. Scala C, Familiari A, Pinas A, Papageorghiou AT, Bhide A, Thilaganathan B, Khalil A. Perinatal and long-term outcome in fetuses diagnosed with isolated unilateral ventriculomegaly: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2017;49:450-9.
  1. Khalil A, Bennet S, Thilaganathan B, Paladini D, Griffiths P, Carvalho JS. Prevalence of prenatal brain abnormalities in fetuses with congenital heart disease: a systematic review. Ultrasound Obstet Gynecol 2016;48:296-307.
  2. Vinayagam D, Patey O, Thilaganathan B, Khalil A. Non-invasive cardiac output monitoring in pregnancy: comparison to echocardiographic assessment. Ultrasound Obstet Gynecol 2017;41:273-82.
  3. Khalil A, A single cervical length measurement at 18-24 weeks is a better predictor of preterm birth than the change in cervical length with gestation. Evid Based Med 2015 Nov 9. pii: ebmed-2015-110259. doi: 10.1136/ebmed-2015-110259. 
  4. D’Antonio F, Khalil A, Zidere V, Carvalho JS. Fetuses with right aortic arch: Multicentre cohort study and meta-analysis. Ultrasound Obstet Gynecol 2016;47:423-32.
  5. KhalilA, Rodgers M, Baschat A, Bhide A, Gratacos E, Hecher K, Kilby MD, Lewi L, Nicolaides K, Oepkes D, Reed K, Raine-Fenning N, Salomon LJ, Sotiradis A, Thilaganathan B, Ville Y; ISUOG Clinical Standards Committee. ISUOG Practice Guidelines: The Role of Ultrasound in Twin Pregnancy. Ultrasound Obstet Gynecol 2016;48:669-70.
  6. Morales-Roselló J,Khalil A. Fetal cerebral redistribution: a marker of compromise regardless of fetal size. Ultrasound Obstet Gynecol 2015;46:385-8.
  7. Scala C, Bhide A, Familiari A, Pagani G, Khalil A, Papageorghiou A, Thilaganathan B. Number of episodes of reduced fetal movement at term: association with adverse perinatal outcome. Am J Obstet Gynecol 2015;213:678.e1-6.
  8. D’AntonioF, Khalil A, Garel C, Pilu G, Rizzo G, Lerman-Sagie T, Bhide A, Thilaganathan B, Manzoli L, Papageorghiou AT. Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal imaging (part 2): neurodevelopmental outcome. Ultrasound Obstet Gynecol 2016;48:28-37.
  9. KhalilA, Morales-Roselló J, Thilaganathan B. Re: Differential effect of intrauterine growth restriction on childhood neurodevelopment: a systematic review. BJOG 2015;122:1850. 
  10. Familiari A, Bhide A, Morlando M, Scala C,Khalil A, Thilaganathan B. Mid-pregnancy fetal biometry, uterine artery Doppler indices and maternal demographic characteristics: role in prediction of small-for-gestational-age birth. Acta Obstet Gynecol Scand 2016;95:238-44.
  11. Khalil A, Morales-Rosello J, Townsend R, Morlando M, Papageorghiou A, Bhide A, Thilaganathan B. Are fetal cerebroplacental ratio and impaired placental perfusion recorded in the third trimester predictors of stillbirth and perinatal loss? Ultrasound Obstet Gynecol 2016;47:74-80.
  12. Khalil AA, Morales-Rosello J, Elsadigg M, Khan N, Papageorghiou A, Bhide A, Thilaganathan B. The association between fetal Doppler and admission to neonatal unit at term. Am J Obstet Gynecol 2015;213:57.e1-7.
  13. Khalil AA, Morales-Rosello J, Morlando M, Hannan H, Bhide A, Papageorghiou A, Thilaganathan B. Is fetal cerebroplacental ratio an independent predictor of intrapartum fetal compromise and neonatal unit admission? Am J Obstet Gynecol 2015;213:54.e1-10.
  14. Khalil A, Maiz N, Garcia-Mandujano R, Penco JM, Nicolaides KH. Longitudinal changes in maternal serum placental growth factor and soluble fms-like tyrosine kinase-1 in women at increased risk of preeclampsia. Ultrasound Obstet Gynecol 2016;47:324-31.
  1. Khalil A, Chaoui R, Lebek H, Esser T, Entezami M, Toms J, Thilaganathan B. Widening of the femoral diaphysis-metaphysis angle at 20-24 weeks: a marker for the detection of achondroplasia prior to the onset of skeletal shortening. Am J Obstet Gynecol 2016;214:291-2.
  2. Morales-Roselló J,Khalil A, Salvi S, Townsend R, Premakumar Y, Perales-Marín A. Abnormal Middle Cerebral Artery Doppler Associates with Spontaneous Preterm Birth in Normally Grown Fetuses. Fetal Diagn Ther 2016;40:41-7.
  3. D’Antonio F, Thilaganathan B, Toms J, Manzoli L, Bhide A, Papageorghiou A, Khalil A. Perinatal outcome after fetoscopic laser surgery for twin-to-twin transfusion syndrome in triplet pregnancies: systematic review. BJOG 2016;123:328-36.
  4. Bhide A, Sankaran S, Moore J, Khalil A, Furneaux E. Ambulatory blood pressure measurements in mid-pregnancy and development of hypertensive pregnancy disorders. Hypertens Pregnancy 2014;33:159-67. 
  5. Virgone C, D’antonio F, Khalil A, Jonh R, Manzoli L, Giuliani S. Accuracy of prenatal ultrasound in detecting jejunal and ileal atresia: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2015;45:523-9.
  6. Khalil A, Maiz N, Garcia-Mandujano R, Elkhouli M, Nicolaides KH. Longitudinal changes in maternal corin and mid-regional proatrial natriuretic peptide in women at risk of pre-eclampsia. Ultrasound Obstet Gynecol 2015;45:190-8. 
  7. Morales-Roselló J, Hervás-Marín D, Stirrup O, Perales-Marín A, Khalil A. International standards for fetal growth: relevance of the advances in ultrasound technology. Ultrasound Obstet Gynecol 2015;46:631-2.
  8. Morales-Roselló J, Khalil A, Morlando M, Hervás-Marín D, Perales-Marín A. Doppler reference values of the fetal vertebral and middle cerebral arteries, at 19-41 weeks gestation. J Matern Fetal Neonatal Med 2015;28:338-43. 
  9. Morales-Roselló J,Khalil A, Perales-Marín A. Fetal tricuspid annulus plane systolic excursion (fTAPSE) at term. Association with cerebroplacental ratio, birth weight and neonatal pH. J Matern Fetal Neonatal Med 2016;29:1636-41.
  10. D’Antonio F, Virgone C, Rizzo G, Khalil A, Baud D, Cohen-Overbeek TE, Kuleva M, Salomon LJ, Flacco ME, Manzoli L, Giuliani S. Prenatal Risk Factors and Outcomes in Gastroschisis: A Meta-Analysis. Pediatrics 2015;136:e159.
  11. Griffin M, Seed PT, Webster L, Myers J, Mackillop L, Simpson N, Anumba D, Khalil A, Denbow M, Sau A, Hinshaw K, Von Dadelszen P, Benton S, Girling J, Redman CW, Chappell LC, Shennan AH. Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small-for-gestational-age infant in women presenting with reduced symphysis-fundus height. Ultrasound Obstet Gynecol 2015;46:182-90.
  12. Thilaganathan B, Khalil A, Melchiorre K. Re: Maternal obesity and excess of fetal growth in pre-eclampsia. BJOG 2015;122:592-3.
  13. Morlando M, Ferrara L, D’Antonio F, Lawin-O’Brien A, Sankaran S, Pasupathy D, Khalil A, Papageorghiou A, Kyle P, Lees C, Thilaganathan B, Bhide A. Dichorionic triplet pregnancies: risk of miscarriage and severe preterm delivery with fetal reduction versus expectant management. Outcomes of a cohort study and systematic review. BJOG 2015;122:1053-60.
  14. Khalil A, Mahmoodian N, Kulkarni A, Homfray T, Papageorghiou A, Bhide A, Thilaganathan B. Estimation of Detection Rates of Aneuploidy in High-Risk Pregnancy Using an Approach Based on Nuchal Translucency and Non-Invasive Prenatal Testing: A Cohort Study. Fetal Diagn Ther 2015;38:254-61.
  1. D’Antonio F, Khalil A, Garel C, Pilu G, Rizzo G, Lerman-Sagie T, Bhide A, Thilaganathan B, Manzoli L, Papageorghiou AT. Systematic review and meta-analysis of isolated posterior fossa malformations on prenatal ultrasound: nomenclature, diagnostic accuracy and associated anomalies. Ultrasound Obstet Gynecol 2016;47:690-7.
  2. John R, D’Antonio F, Khalil A, Bradley S, Giuliani S. Diagnostic Accuracy of Prenatal Ultrasound in Identifying Jejunal and Ileal Atresia. Fetal Diagn Ther 2015;38:142-6.
  3. Khalil AA, Khan N, Bowe S, Familiari A, Papageorghiou A, Bhide A, Thilaganathan B. Discordance in fetal biometry and doppler are independent predictors of the risk of perinatal loss in twin pregnancies. Am J Obstet Gynecol 2015; 213:222.e1-222.e10.
  4. D’Antonio F, Khalil A, Morlando M, Thilaganathan B. Accuracy of Predicting Fetal Loss in Twin Pregnancies Using Gestational Age-Dependent Weight Discordance Cut-Offs: Analysis of the STORK Multiple Pregnancy Cohort. Fetal Diagn Ther 2015;38:22-8.
  5. Morales-Roselló J, Khalil A, Alberola-Rubio J, Hervas-Marín D, Morlando M, Bhide A, Papageorghiou A, Perales-Marín A, Thilaganathan B. Neonatal Acid-Base Status in Term Fetuses: Mathematical Models Investigating Cerebroplacental Ratio and Birth Weight. Fetal Diagn Ther 2015;38:55-60.
  6. Morales-Roselló J, Khalil A, Morlando M, Bhide A, Papageorghiou A, Thilaganathan B. Poor neonatal acid-base status in term fetuses with low cerebroplacental ratio. Ultrasound Obstet Gynecol 2015;45:156-61.
  7. Stirrup OT, Khalil A, D’Antonio F, Thilaganathan B; Southwest Thames Obstetric Research Collaborative (STORK). Fetal growth reference ranges in twin pregnancy: analysis of the STORK multiple pregnancy cohort. Ultrasound Obstet Gynecol 2015;45:301-7.
  8. Pagani G, D’Antonio F, Khalil A, Papageorghiou A, Bhide A, Thilaganathan B. Association between reduced fetal movements at term and first trimester markers of impaired placental development. Placenta 2014;35:606-10.
  9. Khalil A, Morales-Roselló J, Morlando M, Bhide A, Papageorghiou A, Thilaganathan B. Widening of the Fetal Femoral Proximal Diaphyseal-Metaphyseal Angle: A New Ultrasound Finding in Achondroplasia. Ultrasound Obstet Gynecol 2014;44:69-75.
  10. D’Antonio F, Khalil A, Pagani G, Papageorghiou AT, Bhide A, Thilaganathan B. Crown Rump Length Discordance and Adverse Perinatal Outcome in Twin Pregnancies: Systematic Review And Meta-analysis. Ultrasound Obstet Gynecol 2014;44:138-46.
  11. Morales-Roselló J, Khalil A, Morlando M, Papageorghiou A, Bhide A, Thilaganathan B. Changes in fetal Doppler indices as a marker of failure to reach growth potential at term. Ultrasound Obstet Gynecol 2014;43:303-10.
  12. Verlohren S, Melchiorre K, Khalil A, Thilaganathan B. Uterine artery Doppler, birthweight and timing of preeclampsia onset: providing insights into the dual etiology of late-onset preeclampsia. Ultrasound Obstet Gynecol 2014;44:293-8.
  13. Khalil A, D’Antonio F, Dias T, Cooper D, Thilaganathan B. Ultrasound Estimation of Birthweight in Twin Pregnancy: Comparison of Biometry Algorithms in the STORK Multiple Pregnancy Cohort. Ultrasound Obstet Gynecol 2014;44:210-20.
  14. D’Antonio F, Khalil A, Thilaganathan B; Southwest Thames Obstetric Research Collaborative (STORK). Second-trimester discordance and adverse perinatal outcome in twins: the STORK multiple pregnancy cohort. BJOG 2014;121:422-9.  
  1. Iacovella C, Chandrasekaran N, Khalil A, Bhide A, Papageorghiou A, Thilaganathan B. Fetal and Placental Vascular Tumors: Persistent Fetal Hyperdynamic Status Predisposes to Poorer Long Term Neurodevelopmental Outcome. Ultrasound Obstet Gynecol 2014;43:658-61.
  2. Khalil A, Papageorghiou A, Bhide A, Akolekar R, Thilaganathan B. Biparietal diameter at 11 to 13 weeks’ gestation in fetuses with holoprosencephaly. Prenat Diagn 2014;34:134-8.
  3. Pagani G, D’Antonio F, Khalil A, Akolekar R, Papageorghiou A, Bhide A, Thilaganathan B. Association between reduced fetal movements at term and abnormal uterine artery Doppler indices. Ultrasound Obstet Gynecol 2014;43:548-52.
  4. Khalil A, Caric V, Papageorghiou A, Bhide A, Akolekar R, Thilaganathan B. Prenatal prediction of need for ventriculoperitoneal shunt in open spina bifida. Ultrasound Obstet Gynecol 2014;43:159-64.
  5. Khalil A, Cooke PC, Mantovani E, Bhide A, Papageorghiou AT, Thilaganathan B. Outcome of First Trimester Fetal Abdominal Cysts: A Cohort Study and Review of the Literature. Ultrasound Obstet Gynecol 2014;43:413-9.
  6. Khalil A, Maiz N, Garcia-Mandujano R, Elkhouli M, Nicolaides KH. Longitudinal changes in maternal soluble endoglin and angiopoietin-2 in women at risk for pre-eclampsia. Ultrasound Obstet Gynecol 2014;44:402-10.
  7. Khalil A, Nicolaides KH. Fetal heart defects: potential and pitfalls of first-trimester detection. Semin Fetal Neonatal Med 2013;18:251-60.
  8. Chitty LS, Khalil A, Barrett AN, Pajkrt E, Griffin DR, Cole TJ. Safe, accurate, prenatal diagnosis of thanatophoric dysplasia using ultrasound and free fetal DNA. Prenat Diagn 2013;33:416-23.
  9. Khalil A, Suff N, Thilaganathan B, Hurrell A, Cooper D, Carvalho JS. Brain Abnormalities and Neurodevelopmental Delay in Congenital Heart Disease: Systematic Review and Meta-analysis. Ultrasound Obstet Gynecol 2013;43:14-24.
  10. Spencer K, Khalil A, Brown L, Mills I, Horne H. First trimester maternal serum alpha-fetoprotein is not raised in pregnancies with open spina bifida. Prenat Diagn 2014;34:168-71.
  11. Khalil A, Garcia-Mandujano R, Maiz N, Elkhouli M, Nicolaides KH. Longitudinal changes in maternal hemodynamics in a population at risk for pre-eclampsia. Ultrasound Obstet Gynecol 2014;44:197-204.
  12. Khalil A, Garcia-Mandujano R, Maiz N, Elkhouli M, Nicolaides KH. Longitudinal changes in uterine artery Doppler and blood pressure and the risk of pre-eclampsia. Ultrasound Obstet Gynecol 2014;43:541-7.
  13. D’Antonio F, Khalil A, Mantovani E, Thilaganathan B; Southwest Thames Obstetric Research Collaborative. Embryonic growth discordance and early fetal loss: the STORK multiple pregnancy cohort and systematic review. Hum Reprod 2013;28:2621-7.
  14. Pagani G, D’Antonio F, Khalil A, Papageorghiou A, Bhide A, Thilaganathan B. Intrafetal Laser Treatment for Twin Reversed Arterial Perfusion Sequence: A Cohort Study and Meta-Analysis. Ultrasound Obstet Gynecol 2013;42:6-14.
  15. D’Antonio F, Rijo C, Thilaganathan B, Akolekar R, Khalil A, Papageorghiou A, Bhide A. Association between first trimester maternal serum pregnancy associated plasma protein-a and obstetric complications. Prenat Diagn 2013;33:839-47.
  16. D’Antonio F, Khalil A, Dias T, Thilaganathan B; the Southwest Thames Obstetric Research Collaborative (STORK). Crown-rump length discordance and adverse perinatal outcome in twins: analysis of the Southwest Thames Obstetric Research Collaborative (STORK) multiple pregnancy cohort. Ultrasound Obstet Gynecol 2013;41:621-6. 
  17. Khalil A, Coates A, Papageorghiou A, Bhide A, Thilaganathan B. Biparietal diameter at 11-13 weeks’ gestation in fetuses with open spina bifida. Ultrasound Obstet Gynecol 2013;42:409-15.
  18. D’Antonio F, Khalil A, Dias T, Thilaganathan B; the Southwest Thames Obstetric Research Collaborative (STORK). Weight discordance and perinatal mortality in twins: analysis of the STORK multiple pregnancy cohort. Ultrasound Obstet Gynecol 2013;41:643-8.
  19. D’Antonio F, Khalil A, Dias T, Thilaganathan B; the Southwest Thames Obstetric Research Collaborative (STORK). Early fetal loss in monochorionic and dichorionic twin pregnancies: analysis of the STORK multiple pregnancy cohort. Ultrasound Obstet Gynecol 2012;41:632-6.
  20. Khalil A, Nicolaides KH. How to record uterine artery Doppler in the first trimester. Ultrasound Obstet Gynecol 2013;42:478-9.
  21. Khalil A, Syngelaki A, Maiz N, Zinevich Y, Nicolaides KH. Maternal age and adverse pregnancy outcomes: a cohort study. Ultrasound Obstet Gynecol 2013;42:634-43.
  22. Khalil A, Rezende J, Akolekar R, Syngelaki A, Nicolaides KH. Maternal racial origin and adverse pregnancy outcomes: a cohort study. Ultrasound Obstet Gynecol 2012;41:278-85.
  23. Khalil A, Sodre D, Akolekar R, Syngelaki A, ElKhaouli M, Nicolaides K. Maternal hemodynamics at 11-13 weeks of gestation in pregnancies delivering small for gestational age neonates. Fetal Diagn Ther 2012;32:231-8.
  24. Khalil A, Akolekar R, Syngelaki A, Elkhouli M, Nicolaides KH. Maternal hemodyamics at 11-13 weeks of gestation and the risk of pre-eclampsia. Ultrasound Obstet Gynecol 2012;39:401-6.
  25. Khalil A, Garcia-Mandujano R, Chiriac R, Akolekar R, Nicolaides K. Maternal hemodynamics at 11-13 weeks’ gestation in gestational diabetes mellitus. Fetal Diagn Ther 2012;31:216-20.
  26. Khalil A, Akolekar R, Syngelaki A, ElKhouli M, Nicolaides K. Maternal hemodynamics in normal pregnancies at 11-13 weeks’ gestation. Fetal Diagn Ther 2012;32:179-85.
  27. Khalil A, ElKhouli M, Garcia-Mandujano R, Chiriac R, Nicolaides K. Maternal hemodynamics at 11-13 weeks of gestation and preterm birth. Ultrasound Obstet Gynecol 2012;39:401-6.
  28. Khalil A, Tsikas D, Akolekar R, Jordan J, Nicolaides K. Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks’ gestation and preeclampsia: a case control study. J Hum Hypertens 2011;27:38-43.
  29. Khalil A, Arnaoutoglou C, Pacilli M, Szabo A, David AL, Pandya P. Outcome of fetal exomphalos diagnosed at 11-14 weeks of gestation. Ultrasound Obstet Gynecol 2012;39:401-6.
  30. Chitty LS, Griffin DR, Meaney C, Barrett A, Khalil A, Pajkrt E, Cole TJ. New aids for the non-invasive prenatal diagnosis of achondroplasia: dysmorphic features, charts of fetal size and molecular confirmation using cell-free fetal DNA in maternal plasma. Ultrasound Obstet Gynecol 2011;37:283-9.
  31. Cowans NJ, Stamatopoulou A, Khalil A, Spencer K. PP13 as a marker of pre-eclampsia: A two platform comparison study. Placenta 2011;32 Suppl:S37-41.
  1. Khalil A, Pajkrt E, Chitty LS. Early prenatal diagnosis of skeletal anomalies. Prenat Diagn 2011;31:115-24.
  1. Khalil A, Akolekar R, Syngelaki A, Penco JM, Nicolaides KH. Effect of chorionic villus sampling on uterine artery Doppler. Fetal Diagn Ther 2010;28:9-13.
  2. Khalil A, Akolekar R, Pandya P, Syngelaki A, Nicolaides K. Chorionic villus sampling at 11 to 13 weeks of gestation and hypertensive disorders in pregnancy. Obstet Gynecol 2010;116:374-80.
  3. Khalil A, Jauniaux E, Harrington K. The effect of antihypertensive therapy with alpha methyldopa on uterine artery Doppler. Ultrasound Obstet Gynecol 2010;35:688-94.
  4. Khalil A, Spencer K, Cowans NJ, Meiri H, Harrington KF. First trimester markers for the prediction of pre-eclampsia in women with a priori high risk. Ultrasound Obstet Gynecol 2010;35:671-9.
  5. Khalil A, Spencer K, Cowans NJ, Meiri H, Harrington KF. First trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women with a priori high risk. Prenat Diagn 2009;29:781-9.
  6. Khalil A, Jauniaux E, Cooper D, Harrington K. Pulse wave analysis in normal pregnancy: A prospective longitudinal Study. PLoS ONE 2009;4:e6134. doi:10.1371/journal.pone.0006134
  7. Khalil AA, Cooper DJ, Harrington KF. Pulse wave analysis: a preliminary study of a novel technique for the prediction of pre-eclampsia. BJOG 2009;116:268-76.
  8. Khalil A, Jauniaux E, Harrington K. Antihypertensive therapy and central hemodynamics in women with hypertensive disorders in pregnancy: a case control study. Obstet Gynecol 2009;113:646-54.
  9. Khalil A, Jauniaux E, Harrington K, Muttukrishna S. Placental production and maternal serum and urine levels of inhibin A and activin A are modified by antihypertensive therapy in hypertensive disorders of pregnancy. Clin Endocrinol 2009;70:924-31.
  10. Khalil A, Muttukrishna S, Harrington K, Jauniaux E. Effect of antihypertensive therapy with alpha methyldopa on levels of angiogenic factors in pregnancies with hypertensive disorders. PLoS ONE 2008;3:e2766. doi:10.1371/journal.pone.0002766